ASEA partnered with Taueret Laboratories, a leading genetic research laboratory, to conduct an observational study to understand how ASEA REDOX affects the activation of human genes. Taueret Labs believes in advancing medical research through leading edge genomic services.
ASEA 与领先的基因研究实验室 Taueret Laboratories 合作，开展一项观察研究，以了解 REDOX 如何影响人类基因的激活。Taueret 实验室致力于通过领先的基因组服务推动医学研究的发展。ASEA
They have spearheaded projects that have led to gene testing breakthroughs in multiple industries that have the potential to help countless numbers of people.
他们带头开展的项目为多个行业带来了基因检测方面的突破，有可能帮助无数人。
Taueret Labs is led by Dr. Kenneth Ward, MD, a premier researcher in female reproductive medicine and board certified in OB/GYN, Maternal Fetal Medicine, Medical Genetics and Molecular Genetics.
Taueret 实验室由医学博士肯尼思-沃德博士领导，他是女性生殖医学的主要研究者，拥有妇产科、母胎医学、医学遗传学和分子遗传学的认证。
The eight-week human study was reviewed and approved by Quorum Review Independent Review Board, ensuring the ethical integrity, safety, and control of the research study. The study was a randomized double-blind placebo controlled study.
这项为期八周的人体研究经过了 Quorum Review 独立审查委员会的审查和批准，确保了研究的道德完整性、安全性和控制性。该研究是一项随机双盲安慰剂对照研究。
Researchers randomized 60 participants into three groups, 25 in the active group (ASEA REDOX), 25 in the placebo group (saline placebo), and 10 in the control group (did not drink either ASEA REDOX or placebo).
研究人员将 60 名参与者随机分为三组，其中 25 人在活性组（ASEA REDOX），25 人在安慰剂组（生理盐水安慰剂），10 人在对照组（不喝ASEA REDOX 或安慰剂）。
It is important to note that the placebo was the same saline used to create the ASEA REDOX for this study, but did not contain ASEA’s patented redox molecules.
值得注意的是，安慰剂与用于制作ASEA REDOX 的生理盐水相同，但不含ASEA的专利redox 分子。
Of the total 60 participants, 41% were male, 59% were female, the mean age was 35, and they were 92% Caucasian. Each participant, except for the control group, drank 4 ounces of ASEA REDOX or placebo twice daily.
在总共 60 名参与者中，41% 为男性，59% 为女性，平均年龄为 35 岁，92% 为白种人。除对照组外，每位参与者每天两次饮用 4 盎司ASEA REDOX 或安慰剂。
Participants’ blood was drawn at week zero and at week eight. Serum RNA was extracted using a PreAnalytix PAXgene Blood RNA Kit. Gene expression levels were tested using Affymetrix PrimeView Array and differential expression within and between groups analyzed.
参与者在第 0 周和第 8 周抽血。使用 PreAnalytix PAXgene 血液 RNA 试剂盒提取血清 RNA。使用 Affymetrix PrimeView 阵列检测基因表达水平，并分析组内和组间的差异表达。
RESULTS 结果
Results of the eight-week study showed a 20 – 31% difference in gene expression abundance in five genes that are involved in pathway signaling, including regulatory network pathways.
为期八周的研究结果表明，参与通路信号转导（包括调控网络通路）的五个基因的基因表达丰度相差 20%-31% 。
Long-term consumption of ASEA REDOX resulted in stable expression changes at the eight-week time point (figure 1).
长期服用ASEA REDOX，在八周的时间点上，其表达发生了稳定的变化（图 1）。
These genes are key in the health of the individual and play a vital role in five human health areas and dozens of pathways. (figure 2)
这些基因是个人健康的关键，在五个人类健康领域和数十种途径中发挥着重要作用。(图 2）
“These results are unique and exciting. ASEA REDOX is a signaling supplement and the pathways expressed are signaling genes.” – Dr. Kenneth Ward
"这些结果是独特而令人兴奋的。 ASEA REDOX 是一种信号补充剂，所表达的通路就是信号基因"。- 肯尼斯-沃德博士
The genes that expressed significance when comparing the ASEA REDOX group to the placebo group at eight weeks are represented by the symbols below with their accompanying percentages of change shown in the study.
ASEA REDOX 组与安慰剂组在八周后的比较中，表现出显著性的基因用下面的符号表示，其相应的变化百分比显示在研究中。
Pathway signaling genes are unique as they have the potential to influence a multitude of biological responses. Analysis of the five genes was provided through two pathway analysis programs, PANTHER (Protein ANalysis THrough Evolutionary Relationships) and WikiPathways.
通路信号基因很独特，因为它们有可能影响多种生物反应。我们通过两个通路分析程序 PANTHER（通过进化关系分析蛋白质）和 WikiPathways 对这五个基因进行了分析。
An example of a gene product that was expressed in this study that interacts with multiple important pathways is the EGR1 gene.
本研究中表达的与多种重要通路相互作用的基因产物的一个例子是 EGR1 基因。
As shown below (figure 3) this one gene can influence 15 different pathways.
如下图所示（图 3），这一个基因可以影响 15 种不同的途径。
In order to better understand how the genes reacted post-study, the ASEA REDOX group that saw the 20 – 31% change provided blood samples eight weeks post-study.
为了更好地了解基因在研究后的反应，ASEA REDOX 组在研究后八周提供了 20-31% 的血液样本。
The results demonstrated that all the changes seen while on the product had reverted back to their pre-study levels (figure 4).
结果表明，服用该产品期间出现的所有变化都已恢复到研究前的水平（图 4）。
Summary 摘要
- The initial study data suggests that five genes expressed a change in transcript abundance.
初步研究数据表明，有五个基因的转录本丰度发生了变化。 - The ASEA REDOX group saw gene activation results in regulatory pathway related genes that signal dozens of important biological functions.
ASEA REDOX 小组看到了基因激活的结果，即与调控途径相关的基因发出了数十种重要生物功能的信号。 - The ASEA REDOX and the placebo (saline) behaved differently.
ASEA REDOX 和安慰剂（生理盐水）的表现不同。 - There were no harmful changes in the gene expression trends of the participants consuming either beverage during the course of the study. This is representative of long-term safety.
在研究过程中，饮用这两种饮料的参与者的基因表达趋势没有发生有害变化。这代表了长期安全性。 - Daily consumption of ASEA REDOX over eight weeks appears to result in stable expression changes.
ASEA REDOX，每天服用八周，似乎能带来稳定的表达变化。 - Changes in gene expression eight weeks post study in the ASEA REDOX group were no longer observed. This suggests continued use of ASEA REDOX is necessary to sustain the observed gene expression results.
ASEA REDOX 组在研究八周后基因表达不再发生变化。这表明，要维持观察到的基因表达结果，就必须继续使用ASEA REDOX。 - Effects of consuming ASEA REDOX are systemic.
ASEA REDOX 的影响是全身性的。 - Effects are non-specific to race, sex or age, and were observed in all populations tested.
这种影响与种族、性别或年龄无关，在所有受测人群中都能观察到。
